Polynucleotides: Everything You Need to Know

Vicky Eldridge
By Vicky Eldridge

Vicky Eldridge is an award-winning journalist, editor and copywriter, with 18 years’ experience in aesthetics.


At Hamilton Fraser, we are proud to provide insurance cover for the most comprehensive range of cosmetic treatments in aesthetics. We continuously monitor the sector to accommodate new treatments and make sure that we meet our customers’ needs.
 
As an aesthetic practitioner, you will know how important it is to stay ahead of patient trends and respond to innovation in the aesthetics industry. But with the pace of change happening so fast, it can sometimes be difficult to know whether a trend is here to stay, or just a passing fad. 
 
While demand for botulinum toxin, dermal fillers and chemical peels continues to grow, and these are still the most popular treatments amongst our customers, aesthetic practitioners looking to stay at the forefront of medical aesthetics are increasingly incorporating regenerative medicine (polynucleotides) into their practice. Regarded as the ‘gold standard’ in skin regeneration, there has been a rapid surge in the popularity of polynucleotides to meet increasing patient demand. But while they’re a hot topic in aesthetics at the moment, what are they, are they here to stay, and how can Hamilton Fraser help you integrate polynucleotides into your practice? 
What are polynucleotides?
A newly emerging revolutionary tool in regenerative medicine, polynucleotides work to stimulate fibroblasts at a cellular level to encourage restoration and regeneration of the skin from within. Unlike hyaluronic acid dermal fillers, the aim is not purely to add volume, but to regenerate. 
 
Polynucleotides are long chains of nucleotides that make up DNA and RNA molecules. They are derived from fragments of fish DNA (which resemble human DNA), which means they have the ability to function as a biostimulator, kick-starting regeneration in the skin. Not only are they anti-inflammatory, thanks to their antioxidant properties, but they increase collagen production, resulting in a thicker, healthier epidermis. 
What are polynucleotides?
Why are polynucleotides so popular with patients?
Polynucleotides yield far more natural results and carry a lot less risk compared to many other injectables. Because they utilise natural DNA fractions, they are as close to natural as possible, offer some impressive benefits and results, and can be used in a wide range of applications as a rejuvenating treatment for older skin and as a preventative treatment for younger skin. 
 
With patients increasingly focusing on achieving natural-looking results, enhancing individual features by regenerating damage, and more interested in the long-term effects of treatments than a short-term fix, the future looks promising for polynucleotides. 
 
Rejuvenating treatment for older skin
How are polynucleotides used? 
Polynucleotides are being used to reverse the ageing of tissues and repair scarring by tackling the concern from the source, in contrast to the traditional approach, which focuses on treating symptoms. Some of the applications of polynucleotides include Rejuvenating treatment for older skin to treat fine lines and wrinkles preventative treatment for younger skin rehydration for dull skin at any age treating dark circles as an alternative to tear trough fillers strengthening delicate areas of skin such as around the eyes and mouth reducing inflammation to help with conditions such as rosacea treating hyperpigmentation, Sundamage, scarring, stretch marks and acne treating alopecia and hair loss.
In addition to their success rate with these applications, polynucleotides work well alongside other treatments, enhancing their effects, such as by boosting the longevity of anti-wrinkle injections. 
 
What are the potential side effects of polynucleotides? 
 
One of the advantages of polynucelotides is that they have an excellent safety record and are generally highly tolerated. Although the risks and side effects are less than those of other injectable procedures, this will depend on the practitioner’s experience and technique. Patients may experience redness, swelling and bruising but this should settle after one to two days. More serious side effects, such as allergic reactions, are extremely rare. 
 
As with all treatments, it’s important to carry out a thorough pre-treatment consultation to assess the patient’s suitability. Explaining and documenting any potential side effects, and getting signed consent, is just as important as the treatment itself in case you have a claim or complaint made against you. Make sure anything discussed in the consultation is noted, ideally in email form, so that you have an audit trail. It is also best practice to carry out a two-stage consenting process. When you see the patient twice, you can provide them with the details of any risks and benefits at the first appointment and evidence the consent at the second appointment.  
 
How can Hamilton Fraser help you integrate polynucleotides into your clinic? 
 
Hamilton Fraser can provide polynucleotides cover for doctors, dentists, nurses, dental hygienists, dental therapists, pharmacists, paramedics, operating department practitioners and physiotherapists within your medical malpractice insurance policy. Polynucleotides are covered as standard for these medical professionals under mesotherapy skin rejuvenation, provided you have the relevant qualifications to perform this treatment. Training needs to be undertaken with a medical professional. 
 
Learn more about regenerative treatments (polynucleotides). 
If you are looking for insurance to cover polynucleotides, please contact the Hamilton Fraser team on 0800 634 3881 or email cosmeticsales@hamiltonfraser.co.uk
 
Visit our treatment pages to find out more about the treatments we cover. If a specific treatment is not listed, please give us a call to discuss your bespoke requirements. 
This article was written for the Consulting Room Magazine.
 
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