Reviderm ® Intra

Product Summary

Many attempts have been made during past decades to fill wrinkles or scars with biological or artificial implants. Most biological materials are however, reabsorbed within 1 year, where synthetic materials until recently, showed side effects like migration, granuloma formation, late allergic reaction and other unwanted material behaviour.

Reviderm Intra is an injectable implant (flexible Dextran microbeads -- Dextran is a carbohydrate complex, the liquid form was once used in the place of saline in breast implants) 40-60 microns in size. The micro-beads are evenly suspended in a non-animal hyaluronic acid.

This is not a commonly used filler in the U.K. as most practitioners still prefer to use non-permanent, resorbable fillers.


Reviderm IntraWhat does it contain?

Non-animal Hyaluronic acid and Dextran pearls (see picture to the right).


Is a skin test required before treatment?



Is it temporary or permanent?

Long lasting - it is claimed that the Dextran micropsheres completely dissolve over time.


Licenced status

Medical device.


Should be used by

Trained members of the medical profession only.


Product uses

The main indications for use are glabellar frowns, nasolabial and radial lip folds, perioral lines, depressed corners of the mouth, and acne scars.


Not to be used in

Individuals with a known hypersensitivity to hyaluronic acid or dextran beads.

Pregnant or breastfeeding women.

Individuals with a history of autoimmune disease.

Patients who have a tendency to develop hypertrophic scars.


Duration of effect

Reviderm intra is injected subdermally. The volume to be implanted depends on the depth and size of the skin defect or wrinkle.

After the procedure, the hyaluronic acid vehicle will be degraded by the body within 3–6 months. All dextran beads will be totally encapsulated by a fine fibrous capsule. This connective tissue holds the dextran beads in place indefinitely and the process will be completed within 2 – 4 months after injection. As the beads appear to be biodegradable over time, the results may be long lasting but not permanent.


Reported side effects

Transient erythema (redness), swelling, pain, itching, discolouration or tenderness at the implant site.

A small number of patients (one to two percent) may develop an allergic reaction after one or more injections.

Granuloma is a more serious, but rare side effect that may occur with Reviderm intra and is linked with the use of other similar products using synthetic materials.

Granuloma formation may show up as red lumps underneath the skin and may be permanent.



Again, this depends on area treated and how much is required, and the practitioner doing the treatment, but ranges are in the region of:£300 - £400/syringe.