Nanoparticle safety in sunscreens questioned yet again

Posted on the 27 May 2010 at 11:49

Na-nu, na-nu...what?

 

Well it might not be from an episode of Mork & Mindy, but the concept of ‘nanoparticles’ is pretty alien to most people.

 

Wikipedia defines a nanoparticle as;

 

“...a small object that behaves as a whole unit in terms of its transport and properties. It is further classified according to size: in terms of diameter. Nanoparticles are sized between 1 and 100 nanometers. “

 

Any the wiser? No, me neither.

 

Essentially nanoparticles are very, very small particles of a material (about 1/50,000 the width of a human hair) which are somewhere close to the atomic or molecular structure of a substance without being an individual molecule. They are of great scientific interest in many areas of industry at the moment as they often provide interesting and unexpected properties due to their large surface area that a larger particle of the material doesn’t possess.

 

In the last decade, nanoparticles have started to be used in cosmetics and in particular sunscreen products which contain zinc oxide and titanium dioxide used to block UVA1, 2 and UVB, but much controversy reigns over whether they pose health risks in terms of their ability to penetrate cells and tissue when applied to the human body which larger particles could not achieve. There are questions abound as to whether they should therefore be banned from use entirely or discouraged until more scientific knowledge is accrued. Pressure groups such as Friends of the Earth and consumer association Which? have all come out in protest at the use of nanoparticle technology in personal care products, citing the potential risks to human health which are largely unknown it seems.

 

To that end the U.S. Food and Drug Administration (FDA) has received many requests over the last 5 years for it to review and regulate the use of nanotechnology in sunscreens and skincare products, a product area that it doesn’t currently regulate, including a citizen’s petition in 2006 It did however agree to convene a Nanotechnology Task Force to work with other American agencies in an effort to further scientific knowledge in this arena and assist in the setting of safety standards for sunscreens.

 

The Cosmetic, Toiletry, and Fragrance Association (CTFA) in America filed comments with the FDA on the science and regulation of nanoparticles in personal care products in response to the petitions filed with the agency. John Bailey, executive vice president for science at CTFA and former FDA official was quoted at the time as saying:

 

"Nanoparticles in sunscreens are very small particles that have been reviewed and approved by FDA*. They have been used safely and effectively by consumers for decades to protect from harmful UV rays and to prevent skin cancer. These ingredients have properties that provide a greater degree of protection from the sun, are transparent when applied and aesthetically pleasing, and therefore encourage greater consumer acceptance. "

 

[*In 1996, the FDA concluded that smaller, micronized particles of titanium dioxide are not new substances and that there is no evidence demonstrating that these micronized particles are unsafe.]

 

Additionally in 2009, a group call the Environmental Working Group, a non-profit environmental health organisation started its own investigation into sunscreen. They are quoted as saying; “our researchers thought we would ultimately recommend against micronized and nano-sized zinc oxide and titanium dioxide sunscreens. But many months and nearly 400 peer-reviewed studies later, we find ourselves drawing a different conclusion, and recommending some sunscreens that may contain nano-sized ingredients.”

Commentators note that this resulting opinion is based mainly on the risk to health of not using sunscreens containing zinc oxide or titanium dioxide rather than the actual safety of the nanoparticles themselves. The EWG found that people using sunscreens which didn’t contain those ingredients would be exposed to 20% more UVA radiation, the skin cancer causing rays of the sun, so were better off using products containing the nanoteched ingredients than risking not using them.

 

Now, a report has been published by the American Chemical Society Journal, Chemical Research Toxicology in April 2010 which claims to have evidence that nanoparticles of zinc oxide in sunscreens could be toxic (to isolated colon cells) if ingested, when compared to ingesting other particle sizes of the substance.  Although potentially a good study, it is somewhat scare mongering of some media to use this kind of data in respect of the actual safety of using nanoparticle containing sunscreen products properly.

 

The authors themselves  state; “unintended exposure to nano-sized zinc oxide from children accidentally eating sunscreen products is a typical public concern, motivating the study of the effects of nanomaterials in the colon.”

 

Thus, in conclusion, if you eat it, it could do you harm!

 

As most people don’t intend to eat their sunscreen, lipstick, moisturiser or any other topical, personal care products for that matter, or the contents of their kitchen detergent cupboard, this study is of little use in deciding if such products are safe to apply to our skin when venturing outside.

 

Whilst a lack of coherent study, global government interest and consumer education is prevalent the jury will still be out on the long term safety of sunscreens containing nanoparticles and the scare stories will continue.

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Blog Comment(s) [1]

The best scientific knowledge available today says that nanoparticles applied topically in cosmetic formulations have no adverse effects on people. Their safety and effectiveness have been proven in tests under the supervision of independent institutions and experts.

Nano ingredients are not new to cosmetics and have in fact been used safely for a number of years in a variety of applications.

Tracey Beesley | http://www.skinbrands.co.uk