Combination Treatments: How DermaFocus Products Work Alongside Other Modalities

Modern aesthetics is rarely about a single treatment. Patients increasingly seek comprehensive results that address skin health, texture, and structure together. This is why combination treatments are now considered best practice. By integrating regenerative products such as Polynucleotides HPT®, Newest®, and Purasomes with modalities like lasers, microneedling, or hyaluronic acid fillers, practitioners can enhance outcomes and provide care that is both effective and responsible. 

Why Combine Regenerative Treatments? 
Regenerative solutions work at a cellular level, improving skin quality from within. When combined with treatments that resurface, remodel, or restore volume, the benefits reinforce each other. This approach allows practitioners to pair immediate improvements with long-term skin health, delivering results that are natural-looking, durable, and clinically meaningful. 

Polynucleotides HPT® and Skin-Resurfacing Technologies 
Polynucleotides HPT® are highly effective when used alongside lasers or microneedling. While energy-based devices or needling stimulate controlled injury to encourage renewal, polynucleotides support fibroblast activity, collagen and elastin repair, and reduction of oxidative stress. Together, these interventions can accelerate recovery, improve elasticity, and enhance overall texture, often with reduced downtime. 

Newest® and Hyaluronic Acid Fillers 
Newest® combines Polynucleotides HPT® with hyaluronic acid, making it an ideal complement to volumising HA fillers. While fillers restore structure and contour, Newest® improves hydration, elasticity, and radiance. Used in combination, they deliver balanced results that address both form and skin quality, providing patients with outcomes that are comprehensive and refined. 

Purasomes and Regenerative Enhancement 
Exosome-based treatments like Purasomes bring another dimension to combination therapy. When integrated with microneedling, they can be delivered directly into microchannels in the skin, optimising regenerative activity. Combined with treatments that place stress on the skin – such as ablative lasers – Purasomes can support repair, reduce inflammation, and promote more comfortable recovery. 

Safety and Treatment Planning 
Combination treatments should always be approached with careful planning. The timing, sequence, and suitability of each intervention must be tailored to the individual patient. Evidence-based guidance and appropriate training ensure that regenerative products complement other modalities effectively while maintaining patient safety and comfort. 

Supporting Practitioners Through RISE 
At DermaFocus, we recognise that practitioners want confidence in integrating treatments. That is why RISE (Regenerative Innovation and Scientific Education) provides detailed guidance, expert-led insights, and community learning to support safe and effective combination therapies. 

A Holistic Future for Aesthetics 
The future of aesthetics lies in treatments that not only restore appearance but also regenerate tissue. By combining Polynucleotides HPT®, Newest®, and Purasomes with established modalities such as lasers, microneedling, and fillers, practitioners can deliver results that are natural, enduring, and rooted in science. 

Click here to access combination treatment guidance and resources via RISE.