Weight Loss-Related Skin Laxity


n recent years, weight loss medications known as GLP-1 receptor agonists have gained immense popularity as powerful weight loss solutions. Originally developed to treat diabetes, these medications are now widely used for medical and aesthetic weight management, often leading to dramatic and rapid fat reduction. 

Celebrities, influencers and everyday consumers have embraced these drugs as a shortcut to significant weight loss, driving a global trend that is redefining the wellness and aesthetics industry. However, while weight loss offers benefits such as improved metabolic health and a reduced risk of disease, it also has an often overlooked downside: skin laxity. 

Since fat is lost faster than the skin can naturally contract, many individuals experience loose, sagging skin, particularly on the face, neck, arms, and abdomen. The term “Ozempic face” is now widely used to describe this phenomenon.

Why rapid weight loss leads to skin laxity

The skin’s ability to stay firm relies on collagen and elastin, which provide structure and resilience. When weight loss happens gradually, the skin has time to adjust, but with weight loss medications, this often happens too rapidly for the skin to keep up, resulting in:

Since topical treatments such as creams and serums provide minimal improvement and surgical procedures are invasive, expensive and require longer recovery times, a more effective non-invasive approach is needed.

Combination therapy: The most effective approach for post-weight loss skin restoration 
Since rapid weight loss leads to significant skin laxity, finding solutions that effectively restore firmness, stimulate collagen production, and support skin regeneration is crucial. The most effective method is combination therapy, which addresses multiple aspects of skin tightening and rejuvenation. The synergy of energy-based devices and biostimulatory fillers provides the best possible media and long-term results.

The future of ascetic medicine

In the era of rapid weight loss, demand for effective non-invasive skin tightening solutions is higher than ever. The combination of Zaffiro thermo lifting and Neauvia PEGylated fillers delivers superior long-lasting results by tightening, restoring volume and stimulating collagen production, without surgery or downtime.

This results in firmer, more elastic skin, immediate and long-term improvement and safe and natural-looking results. Combination therapies are the future, giving patients the best of both worlds: insert lift and long-term generation. 


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