Are Exosomes the Future of Anti-ageing?

Exosomes, nano-sized vesicles naturally secreted by stem cells, are praised as the latest breakthrough in skin ageing therapy.

With a rising demand for effective anti-ageing solutions, the skincare industry is increasingly intrigued by their potential. The allure of Exosomes lies in their multifaceted approach to tackling ageing concerns. They can help diminish wrinkles, enhance skin texture, and improve elasticity, making them a game-changer in the skincare realm.

Below, explore the various ways Exosomes have been observed by Dr Aggie at the Atelier clinic to enhance skin quality and the different types of Exosomes:

Stimulation of collagen production

Exosomes stimulate fibroblasts to produce collagen, a key protein responsible for maintaining skin firmness and elasticity. By promoting collagen synthesis, exosomes help reduce the appearance of fine lines and wrinkles, resulting in smoother, more youthful-looking skin. Dr Aggie also explains that “Exosomes contain bioactive molecules, such as growth factors, cytokines, and microRNAs, which can modulate cellular signalling pathways involved in collagen synthesis. By delivering these signalling molecules to target cells, Exosomes stimulate the activation of fibroblasts, the cells responsible for producing collagen.”

Hydration of the skin

Dr Aggie tells us that “Exosomes contain bioactive molecules including growth factors, antioxidants and peptides” that enhance the skin's ability to retain moisture. By improving skin hydration, Exosomes help restore the skin's natural barrier function, leading to improved texture and suppleness. Dr Aggie further explains how Exosomes promote skin hydration“ by reducing inflammation, exosomes promote a healthier skin barrier and improve hydration.”

Reduction of oxidative stress

Exosomes possess antioxidant properties that help neutralise free radicals and reduce oxidative stress in the skin. By protecting against environmental damage and inflammation, exosomes contribute to overall skin health and vitality, resulting in a more radiant complexion. Dr Aggie further emphasises that, “Exosomes that contain antioxidants and vital microelements neutralising free radicals reduce the oxidative stress.”

Different types of Exosomes

Dr Aggie explains that there are several different types of Exosomes available; 

1. Plant-based ingredients “that mimic ours in the skin's revitalising process, reducing inflammation, while increasing collagen, elastin, and hyaluronic acid production.” 

2. Synthetic Exosomes which Dr Aggie says “are artificially created in laboratory settings using biomimetic approaches. These Exosomes can be engineered to contain specific bioactive molecules, allowing for precise control over their therapeutic effects.” Dr Aggie also goes on to explain that “there are specifically designed exosomes that help to improve hair growth. “

3. Human-derived Exosomes are another form of Exosomes, but they are not licensed in UK.