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Perfectha® is a highly advanced hyaluronic acid gel filler, developed to fill out wrinkles, hydrate the skin and add volume.
Introduced to the UK in 2011, Perfectha is manufactured and distributed by the French company Laboratory ObvieLine which is a Sinclair IS Pharma company.
Cross-linked (E-brid® technology) non-animal hyaluronic acid gel.
Perfectha contains stabilised non-animal biphasic hyaluronic acid gel, with differing gel particle sizes to treat different indications. Each variant contains 20mg/ml of hyaluronic acid. For example, Perfectha Complement contains 180,000 gel particles/ml and is used to treat superficial wrinkles, while Perfectha Deep contains 8,000 gel particles/ml and is used to treat deep wrinkles and to contour the cheeks, chin and lips.
Obtained by fermentation of biotechnologically modified bacteria.
Perfectha uses E-brid® technology, a cross-linking process that helps to induce the formation of covalent bonds between and within hyaluronic acid particles. The final product features undetectable levels of the cross-linking agent (BDDE).
No allergy test needed.
Hyaluronic acid is completely broken down within the skin over a period of months, eventually leaving no trace of the filler. Treatment results may last between four and twelve months.
Class III medical device, European CE marked in 2007 (Perfectha® FineLines, Perfectha® Derm and Perfectha® Deep), 2010 (Perfectha® Subskin) and 2103 (Perfectha® Complement and Perfectha® Subskin 3x1mL).
Trained members of the medical profession only, including doctors and nurses.
There are five different formulations for Perfectha available which include:
Perfectha Fine Lines 0.5ml (20mg/ml, 180,000 gel particles/ml)
Perfectha Fine Lines is injected into the superficial dermis and is aimed at treating superficial wrinkles, including crow’s feet and perioral wrinkles. It is expected to last 4 to 6 months.
Perfectha Derm 1ml (20 mg/ml, 90,000 gel particles/ml)
Perfectha Derm is injected into the mid dermis and is aimed at treating moderate wrinkles, including frown lines and deeper furrows around the eyes and mouth. It can also be used to add contour and volume to lips. It is expected to last 6 to 12 months.
Perfectha Deep 1ml (0mg/ml, 8,000 gel particles/ml)
Perfectha Deep is injected into the deep dermis and is aimed at treating deep wrinkles, including the nasolabial folds. It can also be used to contour the face, cheeks and chin and to add contour and volume to lips. It is expected to last 8 to 12 months.
Perfectha Subskin 1 x 3ml or 3 x 1ml (20mg/ml, 2,000 gel particles/ml)
Perfectha Subskin is injected (either using a needle or a canula) into the subcutaneous level and can treat skin depressions and scarring. It can also be used to contour the jaw bone, cheeks and chin areas. It is expected to last 12 to 18 months.
Perfectha Complement 0.8ml (20mg/ml, 180,000 gel particles/ml)
Perfectha Complement is injected into the superficial dermis and is used for retouching and alterations following treatments such as botulinum toxins or facial peels. It is expected to last 4 to 6 months.
Individuals known to be intolerant or hypersensitive to hyaluronic acid or hyaluronic acid derivatives, individuals who suffer severe allergic reactions and individuals who suffer from severe inflammatory reactions following treatments.
Results of Perfectha treatment typically last for between four and eighteen months, depending on the specific product used and the indication treated. Hyaluronic acid is safely absorbed by the body over time.
Transient erythema (redness), swelling, pain, itching, discolouration or tenderness at the treatment site. Sensitivity may also increase but this should resolve spontaneously within one or two days following treatment. Swelling and tenderness around the lips may take longer to resolve as this treatment area is more sensitive.
This depends on the area treated and how much is required, and the practitioner doing the treatment, but price ranges are in the region of £100 - £150 per syringe.
Before and after, naso-labial folds in a female
Before and after, naso-labial folds in a male
Before and after, lipodystrophy
Before and after, lips
(Before and after photographs are real patients, your results may differ).
Photos provided courtesy of Laboratory Obvieline (Sinclair IS Pharma)
A prospective study of evaluation of the results achieved with the application of a new gel of hyaluronic acid non animal origin for malar and mental enhancement.
Daniel Vasconcellos Regazzini, MD and James Fares, MD